Manmadha Banam is a dubbed version of the Tamil film Manmadan Ambu. It is a comedy-romance movie in which, Ambujakshi (Trisha Krishnan) is a successful film heroine. Madan (Madhavan) is a rich industrialist and he is the fiancé of Ambujakshi. Madan starts suspecting Ambuja and their relationship is on the verge of break up. Ambuja goes to Europe on a vacation along with her childhood friend (Sangeeta). Madan hires a detective, Bhushanam, (Kamal Hassan), to track her movements as he is suspicious that she has a secret lover.